Tuesday, August 20, 2019
Addiction :: essays research papers
Addiction is compulsive need for and use of a habit-forming substance (as heroin, nicotine, or alcohol). Someone who is addicted or hooked psychologically believes that they cannot function without this substance in their bodies. Drug and alcohol addiction and tear families apart, they change individuals who once were the best people to be around with. Most addictions start at an individuals adolescence age where they just learning who they are and how to fit it. à à à à à Drug addiction can and most of the time leads the individual to stealing from friends and even family. These individual do what ever is in the power to get a hold of their preferred drug. They are capable of hurting those who love them and the ones they love. à à à à à There are many warning signs to addictions which, include the list of the following: à ·Ã à à à à Tolerance. If a person needs increasing amounts of a drug to feel high then they are developing tolerance. à ·Ã à à à à Preoccupation with the drug. A preoccupied person thinks constantly about a drug à ·Ã à à à à Personality changes. Individuals withdraw from their friends and their family. à ·Ã à à à à Solitary use. Individuals often begin using the drug as a social thing but then once they begin to use it alone they can be losing control. à ·Ã à à à à Using drugs as medicine. People often use drugs to take the edge off stressful situation or unpleasant feelings. They may rationalize their use and make it see normal à ·Ã à à à à Continued use despises negative consequences. Drug dependence compels people to use in spite of problem or loss of friends. Some individuals do not become addicted as others do but no one knows why only that it has to do wit individualââ¬â¢s biology.
Monday, August 19, 2019
The Partner by John Grisham Essay -- The Partner by John Grisham
The Partner by John Grisham The Partner is one of John Grisham's best books by far! There was a little more description in The Partner, then in The Firm, but this one had a very slow intro. The book opened with an anonymous man living in Brazil under an unknown name. Patrick Lanigan, now known as Danilo Silva, was living a normal life, not making a big deal about the ninety million dollars he had stolen from his ex-law firm two years ago. Danilo is wanted by his ex-law firm buddies, his client from whom he stole the money, and from the FBI. The people that want him the most were the men hired by the client that lost the ninety million, and they were the ones he was afraid of. He knew if the FBI found him heââ¬â¢d be busted, but also safe, if the other thugs found him, he was dead, all they cared about was the money. One day while he was jogging Danilo is kidnapped and taken to a place where he is tortured with electricity and other devious objects. The FBI received a tip that Patrick Lanigan had been captured, and when the FBI found this team of hitmen, and took Patrick, he had already received burns on his skin and charred his flesh. When Danilo returns to his home town, he once again is Patrick Lanigan, and is forced to face up to all the things he has done in his past. The first thing he does is he gets himself a good lawyer, one he knew from his first life, an old buddy from college. A judge friend, the one who spoke at his funeral, also came to visit Patrick in the ho...
Sunday, August 18, 2019
International Differences Essay -- Argumentative Persuasive Papers
International Differences Did you ever think about what it takes for an international student to come to America for a college education? They have to leave their family and friends, just as we do, but at a much farther distance. I cannot imagine amount of money and time it must take to plan a trip across the world, all for a new, exciting learning experience. Right now, many of us have just moved to a large university and begun a life on our own. It seems like a tough idea to grasp when you are just starting to look at colleges, while still in high school or another point in your life. When the time comes, though, hopefully you will be ready for a change. International students have to live through this same situation, at an even larger scale. I met Jennifer Kuesar the first day I came to Barton Residence Hall, my current residence. I was very nervous, anticipating the time when I would see my living space for the next year. I hoped that there would be some other girls their to meet and talk to about my life at Iowa State University. Luckily, I was in the right place at the right time. Jennifer is a 20-year-old, sophomore, working toward a degree in food science. She was born in Jakarta, Indonesia, and then moved to East Kalimantan, but her family now resides in Jamarinda. She has moved around quite a bit in her life. That may be why her journey to this university has not been as terrifying as it has been for her other friends. Jennifer says that English is a foreign language in Indonesia. You take it as a class, just as an American would take a Spanish class in school. Her first language is Indonesian. Within her family, everyone knows how to speak English except for her mother, as they all travel to the U.S. for b... ...ar, and did not go to all of the events. It did not keep their attention. If Cultural Days and Destination Days occurred at thesame time, the student would have the choice to get involved in one activity, or the other, or both if it could be worked out that way. This would hopefully keep the students more involved and busy in their first week away from home. If Cultural Days could help students to understand new cultures, meet some new friends, and get to know the anxieties of others are mutual, I think that the proposal Jennifer and I thought of could be a success. This idea is good because it is optional and can interest students of all backgrounds. If you choose to participate, you are guaranteed to enjoy yourself, and in turn tell your peers. People should learn more about others around them. It could only make life at Iowa State University easier and better!
Saturday, August 17, 2019
Higher education Essay
â⬠¢Assignment # 2 ââ¬â Comprehensive Case: ââ¬Å"Muffler Magicâ⬠Read the ââ¬Å"Muffler Magicâ⬠case and write a four-to-five (4-5) page report that answers the following: 1. Specify three (3) recommendations about the functions of recruiting, selection, and training that you think Ron Brown should be addressing with his HR manager now. Currently youââ¬â¢re allowing your HR to hire employees without ââ¬Å"carefully screening each and every candidate, checking their references and work ethicâ⬠due to such a high demand of staff. Envitably, youââ¬â¢re higher mediocre applicants for more than mediocre pay and at the risk of your name and overall profitability. Being able to answer minimal questions shouldnââ¬â¢t be enough to be hired as a technician and questions such as ââ¬Å"what do you think the problem is if a 2001 Camery is overheating? What would you do? â⬠should not be enough to secure a position within the company. Muffler Magic offers a range of products and services and engine issues is merely one of the many situations an employee may come across. How do these types of generic questions answer if your applicant is able to fulfill the requirements for ââ¬Å"muffler replacements, oil changes, and brake jobsâ⬠? Obviously, from looking at the handful of situational mishaps youââ¬â¢ve described your HR department is merely hiring whoever walks into the office and in return youââ¬â¢re given inaccurate and potentially life threatening break jobs and repairs out of the companies pocket. This is not acceptable and it is no wonder why the company isnââ¬â¢t profiting. One of the reasons behinds why you donââ¬â¢t necessarily want to adapt or change some crucial points within the company is the money. If you broke down one instance where there was an error made by one of your associates, take the engine for instance a new engine can cost any consumer somewhere in the ballpark of $2,000 to $4,000*ââ¬ânot including the benefits or any extra perks. Now lets say that one of these errors happened in every single store then youââ¬â¢re looking at $50,000+ worth of mistakes coming out of Magic Mufflers pocket (keep in mind that estimated figure is from 1 mistake). With that type of money, I would imagine you could hire and appropriately train quite a few applicants that would be worth your time and money. I would recommend changing your recruiting, selecting and training standards immediately. Starting with the recruiting aspect of Magic Muffler. Instead of allowing the applicants comeà to you, why donââ¬â¢t we go above and beyond and seek the preferred applicant. We can still advertise through local newspapers and internet, but we really should be seeking out those employees that have some kind of responsibility and potential retainability. The one major thing I didnââ¬â¢t see in the recruiting process youââ¬â¢re currently using is zoning in on what type of candidate are you looking forââ¬âin terms of education level and experience level based upon the types of work they will be working on. One of the huge factors to remember is ââ¬Å"Presently, vehicles use high-tech computers and complex electronic systems to monitor the performance of the vehicle. A strong sense of understanding concerning the operation of a vehicle, including how each device interacts, as well as the ability to deal with electronic diagnostic equipment and digital reference manuals is key to the success of a technicianâ⬠(http://www. careeroverview. com/auto-mechanic-careers. html) Therefore, Magic Muffler is in need of a qualified individual that is capable of working with UTD automotive machinery and possible situations that could arise. Therefore Magic Muffler should be spending their money recruiting individuals that ââ¬Å"have successfully completed a vocational training program in automotive service technologyâ⬠(ie:Automotive Youth Education Service (AYES)). For a more advanced position they will need ,in addition to vocational training, stoma kind of ââ¬Å"Postsecondary automotive technician trainingâ⬠whether through a prior company, community college or technical college. Finally other ââ¬Å"qualifications you should be focused on while recruiting is ââ¬Å"the ability to diagnose the source of a problem quickly and accurately, good reasoning ability and a thorough knowledge of automobiles, strong communication and analytical skills and good reading, mathematics, and computer skills to study technical manualsâ⬠with the drive to continuously keep up with new technology and learn new service and repair procedures and specifications. â⬠To find these types of applicants I would recommend some type of college recruiting; starting with on campus recruiting and then continuing the recuriting process with an onsite visit. Continuing with the selection process, I think its quite obvious that we should be focusing on a Personality Profile Analysis, which applicants can perform online and follow this up with a PPA(200 HRM BOOK). If you chose not to go that route you can always focus on tests of cognitive abilities (more specifically aptitude testing and motor/physical abilities). If these testââ¬â¢s pan out then we should go forward with a background check/reference check. This may seem to be an overwhelming process, but finding the perfect candidates is essential to low turnover rates and high satisfaction level across the board. The next step is to select the applicants that you are satisfied with their performance on the tests, interview and background check. After applicants are chosen and hired, we need to start with an orientation of the company and its overall goals and next is training. Although OTJ training does offer a lot to the employee it is not enough for these types of positions. Considering car technology is constantly advancing there needs to a need to continuously further your mechanics knowledge. As a responsible employer you should send your ââ¬Å"experienced automotive service technicians to manufacturer training centers to learn to repair new models or to receive special training in the repair of components, such as electronic fuel injection or air-conditionersâ⬠and even beginner mechanics who show potential may be sent ââ¬Å"to manufacturer-sponsored technician training programs to upgrade or maintain employeesââ¬â¢ skillsâ⬠. There are of course crucial training necessary, which cannot be offered OTJ and that is electronics training. This is vital because electrical components, or a series of related components, account for nearly all malfunctions in modern vehiclesâ⬠. As the employee continues to thrive the company should offer additional training for possible certifications or advancement opportunities. For example: the ââ¬Å"ASE certification has become a standard credential for automotive service technicians. While not mandatory for work in automotive service, certification is common for all experienced technicians in large, urban areas. Certification is available in eight different areas of automotive service, such as electrical systems, engine repair, brake systems, suspension and steering, and heating and air-conditioning. For certification in each area, technicians must have at least 2 years of experience and pass the examination. Completion of an automotive training program in high school, vocational or trade school, or community or junior college may be substituted for 1 year of experience. For ASE certification as a Master Automobile Technician, technicians must pass all eight examinationsâ⬠. *http://www. ehow. com/facts_4830630_cost-car-engine-replacement. html 2. Write three (3) questions for a structured interview form that Ron Brownââ¬â¢s service center managers can use to interview experienced technicians. (Note: do not list possible answers. ) As I had said previously asking generic questions are not going to offer you the results in which most employers desire. There are a couple of things that should be kept in mind when creating these questions such as; which type of questions would be more effective in displaying the qualities Muffler Magic desires? Considering HR already has a lot to do with the hiring process, I think the appropriate form of interview would be a structured situational interview. After analyzing the positions and rating the jobs main duties, we would need to create questions reflecting such duties and daily knowledge to perform them. Three questions I would use to ââ¬Å"test the watersâ⬠would be: What training(classroom or on the job), have you had with engine, transmission or brake diagnostic equipment? Identify the diagnostic program and was it computer and software based? Have you worked with engine, transmission or brake diagnostic equipment ââ¬â computer and software? What was the diagnostic program and what was your involvement? What experience, knowledge, and skill do you have with air brake systems, anti lock, and heavy-duty truck suspensions? Relate your experience and describe your skills working with school bus, heavy-duty trucks, light duty pick-up truck, and van bodies/Relate your experience and describe your skills working with heavy and medium-duty diesel and gasoline-powered engines and light-duty pick-up truck and van engines. (www. msbo. org/library/HumanRes/Interview/Mech. doc).
Friday, August 16, 2019
Whether the Burgess land use model is still relevant in the modern day
Urban land use models are designed to help us understand how towns develop. Although towns and cities have no exact match, the models are designed to show that every urban area has its similarities. Since models rarely take into account things like hills and rivers, there are no guarantees that the model will be completely accurate. I am using the Burgess model because it was one of the most successful land use models- it may well be similarly successful in the modern town. A man called E.W Burgess designed an Urban Land use model, naming it after himself. It was designed in his home country of America, in the city of Chicago. This is what he designed: Burgess' theory was that people competed for limited amounts of space. Only people who that the zones were arranged concentrically, different in age and character. Burgess believed that the housing became newer, and the residents became wealthier, the further they got from the CBD. The people who could afford the best land got it, people like businessmen. The poorest groups were left with the worst locations. Burgess believed that different zones of the city had different functions. These are the sections of the city that he identified: * Central business district ââ¬â contains the major shops and offices, and is the centre for commerce, entertainment and transport. * Wholesale light industry- This is where the oldest housing in the city is. Such housing is usually deteriorating into slum property. Some areas are also being taken over by light industry. The locals tend to be immigrants or poorer social groups. * Low class residential- Inhabited by people who have managed to escape from the previous zone. They work in nearby factories, and have no choice but to live there so they can get to work quickly and cheaply. * Medium class residential- The housing is of a better quality, and is mostly semi detached and council estates. * High class residential- Occupied by people who can afford the most expensive properties and the high cost of properties, and the high cost of commuting. This zone also includes the commuter villages beyond the edge of the city, although there were few in Burgess' time. The Burgess model is also linked to the bid-rent model. The amount of money different land users are willing to pay for the land depends on their location- the CBD has the most expensive rents. It is the most accessible area as most transport services are focused on the city centre, and main roads meet here. The more accessible a location, then the easier it is to get there. Therefore, people prefer to have work locations that people can access easily, and are also prepared to pay more for them. The Burgess Model also ignores the fact that nearly all towns are affected by physical features such as rivers, lakes and hills. It also ignores heavy industries, and housing redevelopment. Also, in 1924, there was not so much dependence on transport as there is today. Other weaknesses in the model include the criticism that in reality, zones do not just end, and the next one begins. Zones overflow, and the model is designed for highly developed cities such as Chicago, and not 3rd world cities that you might find in Ethiopia and Sudan. Therefore, the model is not universally correct. Hypothesis 1. Land use changes with increasing distance from the centre of Blaydon. This statement fits in with the Burgess model, as Burgess claimed that the land near the CBD will be densely populated and tightly fitted, whilst the land further out of town will have more room for things like gardens. Houses will be terraced near the town centre, and semi detatched on the outskirts. This statement fits in with Burgess' Bid Rent Model, as he claimed that land in the centre of the town was more useful and therefore expensive, so less people would be able to afford big gardens. This hypothesis should be true, because in reality most towns grow from the centre, and will therefore have many buildings squashed into a small section of land near the middle, but towards the countryside there is more free space Hypothesis 2. Housing age will become younger with increasing distance from the centre of Blaydon. This theory fits into the burgess model because the further you are from the city centre the younger the houses will be because the growth of cities are from the CBD so the houses on the outskirts will be the youngest. The CBD was built first in the beginning of the development of Blaydon. This means that houses will be built after the early developments. This process will continue until there is no land to build on. This theory means that houses will be younger as you progress further form the CBD. The hypothesis should be true because the Burgess model claims city growth occurred in the CBD first then grew outwards form there. Hypothesis 3 The quality of life will improve with increasing distance from the CBD of Blaydon. This theory also fits into the burgess model because as you get further away from the CBD the environment qualities should increase and also better housing materials will be available. Hypothesis 2 links with this hypothesis because as the houses become younger, they will become more modern and better building methods will be being used. Quality of life will increase due to the steady increase of size in houses as you progress further from the CBD. Bigger houses mean more money and better quality of life. For example, big gardens and garages accompanied with driveways. In my view this is a better quality of life compared to terraced houses with no gardens. This hypothesis should be true because the house age will decrease and quality of life will increase as you move further form the CBD. Also the environment won't be as bad because the roads and air will be less congested.
Biocon â⬠Case Assignment Questions Essay
1. Assuming Biocon receives approval for BIOMAb, should it launch the drug immediately or conduct phase 3 trials before launch? Elaborate the various elements of your action plan. If Biocon receives approval for BIOMAb, the management team will need to carefully consider what the best course of action is moving forward. If the company elects to launch the drug immediately, they will be able to have the first mover advantage, reaching the market before their closest competitor, Erbitux. BIOMAb will also be able to put themselves on the map as they would be the first ever, proprietary drug developed and marked by an Indian firm for Indian patients. The Indian regulatory authorities may also cause a lengthy Phase 3 trial due to their lack of experience with bringing a proprietary drug to market, as evidenced during BIOMAbââ¬â¢s Phase 2 trials. However, even with all of the above listed considerations in mind, Biocon should conduct the phase 3 trials before launching the BIOMAb. BIOMA b is a superior product to Erbitux, as shown in the 100% response rate when combined with chemo and radiotherapy. There are also fewer side affects, a more patient friendly treatment plan, and BIOMAb will be able to offer the drug at a discounted price. Even if BIOMAb is not able to be the first drug to the market, they will be able to make up for those potential loses in the long run. BIOMAb will be entering this marketplace for the first time, and the company will want to enter the market with as strong of a message as possible. BIOMAb is entering this market for the long run, and overcoming any perceptions of shortcuts, lack of quality, or anything less than cutting edge will last well beyond the life of the BIOMAb product. There are only 300 oncologists in this market Biocon cannot afford to miss. While awaiting Phase 3 approval, Biocon can roll out its direct sales force, offering its suite of generic oncology drugs. This waiting period will give the sales force an opportunity to develop roots in the marketplace and to raise awareness of BIOMAb before it is even on the market. The Phase 3 approval process will serve as an advantageous ramp up time so that Biocon is fully prepared to enter the marketplace on better footing with BIOMAb. This time will also enable Biocon to better develop the infrastructure they will need toà optimize its direct distribution channel. Biocon is a new player in bringing a new drug to the market and they will want to ensure that the quality of their product is maintained from the manufacturing floor into the doctorââ¬â¢s office. Assuming that BIOMAb indeed loses its first mover advantage, its value proposition will be its results, which are dependent on properly controlled product. Biocon wants to become a permanent fixture in this market and the company needs to do everything in its power to deliver its value proposition of innovation, quality, and affordability. 1. How big is the current and future market opportunity in BIOMAb? The current market opportunity that Biocon is currently targeting with BIOMAb is composed of the Head and Neck cancer patients within India. More specifically, Biocon is focused, in the short term, on those Head and Neck cancer patients that can afford to pay, estimated at 1,900 patients. These patients will be the ones officially marketed to, but given the Indianââ¬â¢s markets preponderance for using drugs ââ¬Å"off the labelâ⬠, the unofficial market can be target at all cancer patients in India that currently able to afford treatment, 7,114 patients. Given Indiaââ¬â¢s continued economic growth rate (9% annually) and ever expanding population base (1.4%), all of the preceding numbers are certain to grow in the relatively short term. The compounded impact of these different rates will cause these India based estimates to grow exponentially year over year. In the long run, BIOMAb in India is just the tip of the iceberg. CIMAB and Bioconââ¬â¢s current joint venture is to develop and market the molecule on the Indian subcontinent. If Biocon is able to thoroughly manage and develop all aspects of the supply chain (manufacturing, distribution, sales, marketing, etc), Biocon would have good reason to go back to the negotiating table with CIMAB. The success of CIMABââ¬â¢s other partner, YM Bioscience, is not guaranteed and there is no reason that Biocon cannot unseat them in the long run. If Biocon is able to achieve this, along with the Phase 3 trials, the worldwide Head and Cancer would be open to the company, to say nothing for the ââ¬Å"off labelâ⬠prescriptions. Given the worldwide population growth, economic expansion, and aging populations, the long-term market for BIOMAb is practically limitless. 3. Who is the buyer for BIOMAb? What is the decision making unit in this case? What are the benefits that each member of the decision making unit seeks from BIOMAb? The buyer for BIOMAb is (are) the income provider(s) of the family, whose member (s) has (have) been affected by head and neck cancer or another indication, since off-label usage is very common in India. The structure of Indiaââ¬â¢s health care system is such that it is estimated that 95% of BIOMAbââ¬â¢s patients (end users) are going to be self-paying. Therefore, the cost of treatment will be transferred to the earning member of the family. Adult patients have the right to make treatment decisions for themselves, so patients and their families are the decision makers for BIOMAb in this case. As the case states, the oncology doctors are the main influencers, as they diagnose and make ultimate recommendations to their patients as to how extensive the treatment should be. The benefits that each member of the decision making unit (i.e. patients and their families) seeks include BIOMAbââ¬â¢s effectiveness in the treatment of head and neck cancer in conjunction with radio and che motherapy, minimal side-effects (immediate side effects, as well as those that might be associated with long-term use), and drugââ¬â¢s affordability. Should phase-2 trials be conducted by Biocon for other indications, the patients will also want to seek same benefits from the drug for other types of cancer. Based on the information provided in the case, BIOMAbââ¬â¢s effectiveness and minimized side effects are a given. After all, phase-2 trials proved that the tumor was killed 100% of the time when the drug was used in combination with radio and chemotherapy. Moreover, unlike competition, BIOMAb did not produce skin rashes because due to the drugââ¬â¢s unique formula. An important factor will be affordability. Wealth distribution is very uneven in India, and 1/4 of the nationââ¬â¢s population earns less than the government-specified poverty threshold of $0.40/day (Wikipedia). The patients, as well as their doctors, will want to make sure that they can afford to complete treatment to ensure best possible outcome. BIOMAb has a tremendous advantage in this category compared to Erbitux, as it calls for a definite (i.e. six-dose) treatment cycle; total treatment cost can thus be effectively quantified. Another benefit thatà patients will be seeking is the ability of BIOMAbââ¬â¢s sales reps to educate them and their families. Although this is not one of the drugââ¬â¢s literal benefits, it will be a crucial factor since patientsââ¬â¢ face time with doctors and specialists is very limited in India. Pre-educating end users and their families on the benefits, side effects, and other specifics of the drug will ensure that oncologistsââ¬â¢ time with each patient is maximized. 4. Develop a detailed launch plan for BIOMAb. Provide your rationale for the product portfolio, pricing, channel, and communication decisions. Bioconââ¬â¢s launch of BIOMAb is complicated by several factors. The first of these is the lack of phase 3 clinical trials, which would theoretically provide more evidence of the drugââ¬â¢s efficacy and safety on a larger patient pool. This is complicated by the fact that BIOMAbââ¬â¢s competitor comes in the form of a drug called Erbitux, which does have phase 3 trials completed and global acclaim. Bioconââ¬â¢s fear is that if they do not launch before Erbitux, they will lose the first to market advantage they feel necessary to succeed. In this case Biocon should take the time to complete phase 3 clinical trials on the basis of what patients and their families expect from a cancer drug. It was already stated that Erbitux had worldwide acceptance due to having extensive trials not limited to head and neck cancer that proved it was b oth safe and effective. In the eyes of the consumer the single most important concern here is that the drugs are going to work and that death can be avoided. Being first to market has the risk of offering only a temporary advantage until Erbitux actually becomes available. At this point if phase 3 trials are finally completed and the results are not favorable there would be severe consumer backlash and possibly action from the government. Finally, Biocon mentioned being able to appeal to doctorââ¬â¢s via existing relationships in order to get their product sold. Realistically, doctors care more about clinical trials as a means of deciding what drugs to offer. By moving forward with phase 3 trials Biocon would have real data to give these doctorââ¬â¢s the ââ¬Å"hard sell.â⬠The strategy is not just to maximize profit, but build a sustainable brand built on trust and results in the pharmaceutical industry. Building upon that is the question of whether or not to sell generics in addition to BIOMAb and when to sell them. The argument given was that selling generics would give the sales force good experience and at theà same time build a solid revenue base. Biocon should indeed take this route for these very reasons. This will allow them to still bring in revenue while the phase 3 trials of BIOMAb take place. Once the trials are complete, selling them alongside BIOMAb will allow them to capture more of the market when in front of doctors who want to have offerings for price conscious patients. On top of the first two concerns is the issue of price and what impact it would have on both market size due to affordability and perceived quality in comparison to Erbitux. Biocon, after confirmation of the extraordinarily high effectiveness of BIOMAb should charge $6000-7000 per dose or rather whatever would be equivalent to a few steps more than Erbitux. Bioconââ¬â¢s CEO desires to build a brand not based on low price but rather the value provided by the products. The hindrance to this route of course is the Indian cultural perception of what the price should be and the fact that many people cannot afford such cost. However, Biocon is alread y well aware that their effective target market is small so for those people the price is potentially less important. However, Biocon can market the fact that it is a six dose treatment path rather than indefinite dosages like Erbitux so in the long term people save money. Additionally they can get creative here and offer something like Walmartââ¬â¢s layaway program. Patients can agree to pay in equal installments up until their dosing day. On that final day when payment is received they are administered the dose. Payments for the next dose begin and the cycle repeats until the dosage time. Additionally, Biocon is concerned about the sales methodology with regards to going through the usual channels of CFAs, wholesalers, and pharmacies or selling it directly to doctors. By going through the typical channels they have the advantage of reaching more doctors who have existing relationships with certain sellers. In this case though, it would fit more with their overarching strategy to sell direct. The higher cost of the drug would be less apparent when not being sold side by side with competitor drugs through a pharmacy or wholesaler. This would also allow Biocon to sell the generic drugs and BIOMAb side by side as a complete market solution for price conscious people. The savings from not having a middleman can be passed on to the doctors via multi-patient discounts or similar. Finally, the quality of the product could be ensured since BIOMAb requires such delicate handling. This is important for the Biocon brand image moving forward asà there can be no slip ups when it comes to delivering a product critical to treatment of cancer. The direct sales also tie in with overall marketing communication planning since Biocon would not only control distribution of the product, but also the sales communication. Biocon should take this time during sales to educate doctors on the results of the phase 3 trials and provide materials for patients that explain the availability of Biocon reps during their treatment cycles. Biocon reps, as mentioned in the case, should educate the patient on their product and provide other helpful cancer information and family services in the form of support group references, etc. 5. How has Bioconââ¬â¢s strategy and positioning evolved over the years? What role does BIOMAb play in Bioconââ¬â¢s overall strategy? Bioconââ¬â¢s strategy and positioning have greatly evolved over the years. The company started as an enzyme manufacturing company that exported its products from India to the United States and European food processing industry. During this time the company developed an expertise in various fermentation processes. The company soon realized that the global enzyme market was limited to about $1 billion and decided to change its strategy and position itself to compete in the biopharmaceutical market, which was a $10 billion dollar market that was rapidly approaching $80 billion. Biocon was positioned nicely to move into the space and compete in the generic drug sector. They were particularly positioned well to manufacture statins. Statins were a great fit for them because they were small molecules that were easy to manufacture and Biocon already p ossessed the technical capability to do so drawing on its strength in the fermentation process and enzyme manufacturing. This short-term strategy to enter the market focused on developing globally competitive processes that relied on their existing expertise to manufacture drugs whose patents were expiring. After successfully entering into the pharmaceutical market through statins, the company was ready to continue on a growth path and move on to their medium/long term phase by entering into larger molecules in the form of insulin. Again, Biocon identified a large and rapidly growing market where they saw their expertise in fermentation giving them an edge and ability to compete. The results were consistent with theirà first direction change and they were again very successful gaining over 10% of the Indian insulin market share. During this phase of their strategy they partnered with Clinigene to conduct clinical trials comparing it to the market leaders. The current phase of Biocomââ¬â¢s strategy is to shift the companyââ¬â¢s focus to the development of proprietary drugs. Management again saw that the market they were competing in would soon shrink due to the maturing of the Indian drug market and they would experience enormous price pressure as a result. Their vision for the company was to develop drugs that no other companies had yet succeeded in bringing to market, and in doing so reaping the benefits of the huge payoff. BIOMAb is the essence of the final and long-term stages of Bioconââ¬â¢s overall strategy. They are using their collaborative strategy to partner with CIMAB thus giving Biocon the opportunity to develop and market the molecule. This is a huge step towards the long-term goal of moving the company to a discovery and development focused biotech firm. BIOMAb is very important to this next phase of the companyââ¬â¢s growth. In the past they have relied on their expertise and experience carrying over from the enzyme development background. However in this next phase they are entering into uncharted territory and as a result will need to prove they have the capability to adapt their expertise and continue to be successful in areas that are outside of their experience scope. The success of the BIOMAb phase of Bioconââ¬â¢s overall strategy will be key to the future of the company and could indicate that the strategy they have in place will continue to provide the growth and profitability they seek as a biotech firm.
Thursday, August 15, 2019
Positive Behavior Essay
Reinforcement is a consequence following a behavior that could increase the probability of the behavior (Cooper, Heron, & Heward, 2007). Reinforcement helps the behavior to be strong enough that it can occur naturally within its oneââ¬â¢s environment or can be a part of an intervention plan that teaches new behaviors (Sulzer-Azaroff & Mayor, 1991). Reinforcement is an important concept in operant conditioning and an important part of learning process. B. F. Skinner accepted this technique to modify reinforcement and punishment as well as extinction reinforcement. It increases a negative behavior, or a positive behavior. In Operant Learning, there are two types of behaviors positive and negative. Reinforcement is something that is part of everyoneââ¬â¢s life and rewards are given to enforce positive behaviors. Positive reinforcement is something that is done to increase a response from someone. Educators are often involved in positive reinforcement. It helps the students give the desired behavior that is desired by the teacher. Teachers can impact studentââ¬â¢s life positively by dealing with their behavior and by using a reward system. Being an Educator, there must be stability to effectively manage a classroom of students. Sometimes being faced with challenges in managing a studentââ¬â¢s behavior becomes overwhelming especially students with behavior problems. Students are often very hard to teach and to get them focused on the information thatââ¬â¢s being given to them because of the disruptive behaviors, but having some type of intervention plan in place helps to deal with the behavior problems. Although, teachers like to think they can handle things on their own sometimes before going to an administrator for an discipline referral, but because of the problems behavior sometimes being so bad, the student has to get involved with the discipline principal. The behavior could cause suspension from school in-school or out-of-school for a period of time awaiting a hearing. However, positive reinforcement does work for some students in the classroom. In my classroom environment the students gets positive reinforcement by letting them go to the computer lab, watch an educational movie, library, free time, or play music while they work and giving small snacks. These are some of the things that we do for positive reinforcement in the classroom. If positive reinforcement worked for everyone it would be a good thing, but some students do not care to be rewarded for good behavior. However, every student should want to do the right thing and not depend on someone giving them something in order to do well. Negative reinforcement is also a theory of Operant Learning. According to B. F. Skinnerââ¬â¢s( 1953) theory on ââ¬Å"operant conditioningâ⬠Skinner says that to be rewarded has more effect if it does not happen. If one was rewarded constantly the effect would be greater than the rewards that are usually given. If a student doesnââ¬â¢t know when they are being rewarded, they will control and behave themselves more so than anyone who knows the time the rewards are given out. Negative reinforcement is when certain incentives or items are removed after a particular behavior is exhibited. Although it is very unlikely that the behavior may not ever happen again, it is decreased. The negative behavior is increased if a student is stopping, moving or avoiding a negative outcome. It should never be thought of as a punishment. Positive reinforcement is always adding something positive to increase the behavior, but negative reinforcement is taking something that is negative to increase a behavior. Negative reinforcement is also when you do something to keep from being punished for it. An example is if ââ¬Å"I nagged my son about keeping his room clean and he cleans it to avoid me nagging him to clean it. â⬠Reinforcement is something that happens all the time in everyoneââ¬â¢s everyday life. Making a plan for a child that is in special education is very important. To set the goals and objectives, it has to be in written form. To write a plan for setting goals and objectives takes some thought. First of all one must know what an objective is. Since I have been working in the education field, I have had to learn many things. I learned while sitting in an IEP that the teacher must have goals and objectives for the student. The objective gives information of what you want to learn and to be able to show evidence of what you have learned. The objective is important and it must be well taught to help with the evaluating content of the goals. It leaves not enough room for reason. In writing an objective there are uniqueness that should be communicated and they are the accomplishment of an objective. This is a statement of what is anticipated of the learner. Circumstances are actually what the student can do or how the task can be performed. The standard of the objective tells how the student performed the assignment so that it will be acknowledged. Writing objectives should be about how much or how well of what someone will do and by when. For example; ââ¬Å"Alicia will show respect for others, her peers and adults, her ideas, thoughts, opinion, personal space and property. â⬠Alicia should do this independently 90% of the time. Since Alicia is having problems with respecting others, she has to sit away from the group until she apologizes to all of her teachers and peers. Once she does this, she can return back to the group. Alicia likes being with the group, so she finally decides to apologize to everyone. The data was collected by Informal Assessment and Data Collection. Another example would be Alicia needs to follow directions without arguing with the teacher 1 out of 4 times a day as measured by observation, weekly observation and charting the outcome. Everything we do have a consequence whether itââ¬â¢s positive or negative. However, to get a positive stimulus one must increase the behavior to something positive. To get a negative behavior, do something that is not acceptable. It is always wise to try and increase the studentââ¬â¢s behavior by positive reinforcement and definitely not by punishment. Doing something that is positive to decrease the negative behavior is always the right thing to do. Reinforcements of both behaviors are something that is done on a daily basis of everyday life. Today because people operate by their environment, (Martin & Pear, 1999) we all look for reinforcement in our lives rather itââ¬â¢s at work, with our friends, or family. All behaviors eventually become a way of growth. As for reinforcement, it will be more successful if the intensity and the magnitude of enforcers is greater ( Mittenberger, 2008). So, the bottom line is that Positive Reinforcement should be used in the classroom to help those students that are experiencing behavior problems. Special Education Teachers should take into consideration of positive reinforcement to better help their students to be successful.
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